Organic Chemistry II(2.0 credits)
|Course Type||:||Basic Specialized Courses|
|Starts 1||:||2 Spring Semester|
|Lecturer||:||Jiyoung SHIN Professor|
|This course was designed to promote an understanding of introductory organic chemistry and to help students build a logical framework for understanding fundamental organic chemistry. The primary purpose of this course is to acquire a logical framework for understanding fundamental organic chemistry. This framework influences for chemical reactions of the organic molecules having π-bonds. Based on the knowledge of the course contents, the participants are expected to understand organic reaction sequences happening with unsaturated organic molecules, including aromatic compounds, and solve the progressive problems sequentially.|
|Fundamental Chemistry I and II, and Organic Chemistry I|
|Class 1. Electron Configuration of Unsaturated Hydrocarbons and Their Reaction Trends --- Difference of Reactivity between Saturated and Unsaturated Aliphatic Hydrocarbons and Aromatic Hydrocarbons.
Class 2. Nuclear Magnetic Resonance (NMR) Spectroscopy of Organic Molecules --- Level of Energy Source for Various Spectroscopy; Larmor Frequency and Quantized Energy; Spin Spinning and Applied Magnetic Field; Zeeman Effect and Resonances; Shielding and Deshielding; Downfield and Upfield; Chemical Shifts, Integration, and Peak Splitting; [N+1] rule.
Class 3. Preparations of Alkenes and Sequence of Electrophilic Additions of Alkenes --- Potential Energy Stability of Unsaturated Aliphatic Compounds and Electrophilic Additions; Preparations by E2 Elimination and Dehydration; Hydrogenation; Halogenations (toward Monohaloalkane, Dihaloalkane, Halohydrin, and Allylic halide) of Simple Alkenes and Conjugated Dienes.
Class 4. Electrophilic Additions of Alkenes --- Hydration; Carbene Addition; Oxidation; Radical Addition; Heck Coupling; Polymerization.
Class 5. Assessment of the Classes 1-4 with Practice Problems.
Class 6. Reactions of delocalized pai-systems (Diels-Alder Reactions and Electrocyclization) --- Efficient Dienes and Dienophiles; Stereochemistry in Diels-Alder Reactions (Endo/Exo cycloadditions and Endo Rule); Thermal and Photochemical Cyclization for Even- and Odd-Numbered Double Bonds.
Class 7. Preparations of Alkynes and Sequence of Electrophilic Additions of Alkenes --- Hydrogenation; Halogenation; Hydration.
Class 8. Delocalized π-Systems and Reactivity of Benzene --- Stability of Extended Conjugations and the Electron Configuration of Delocalized π-Systems (Nonaromatic/Aromatic/Antiaromatic Compounds); Projection of Resonances.
Class 9. The reaction of Benzene --- Electrophilic Aromatic Substitutions (Halogenation, Nitration, Sulfonation, Friedel-Crafts Alkylation, Friedel-Crafts Acylation, Wolff-Kishner and Clemmensen Reductions).
Class 10. Assessment of the Classes 6-9 with Practice Problems.
Class 11. Electrophilic Substitutions of Substituted Benzenes --- ortho & para-Directing and meta-Directing Groups and the Reactivities
Class 12. Nucleophilic Substitutions of Benzene (via Benzyne Formation or through Inductive Effects of Substituents).
Class 13. Preparations of Multiply Substituted Benzenes --- Protection/Deprotection of amine; Reduction/Oxidation.
Class 14. Electrophilic Substitutions of Fused Aromatic Compounds (Naphthalene and Anthracene).
Class 15. Assessment of the Overall Classes (1-14) with Practice Problems.
|Organic Chemistry: Structure and Function (Eighth Edition), Peter K. Vollhardt and Neil Schore, (W. H. Freeman and Company), New York, 2018, Chapters 11-16 and 22|
|Organic Chemistry (second edition), Jonathan Clayden, Nick Greeves, and Stuart Warren (Oxford University Press), 2012 ISBN-10:0199270295.|
|Examination [total 70%: two midterms (20% for each) and one final (30%)] and Assignment of Homework and Attendances(30%): S(x≧90), A(90>x≧80), B(80>x≧70), C(70>x≧60), and F(60>x) for the students who entered earlier than 2020; A+(≧95), A(95>x≧x80), B(80>x≧70), C(70>x≧65), C-(65>x≧60), and F(60＞x) for the students who entered in 2020 or later than 2020. The assessment methods will be reconsidered due to the change of the pandemic condition.|
|Submission of the "Course Withdrawal Request Form is necessary to withdraw the course. The student needs to contact the course instructor when the student wants to withdraw from the course. No submission of sickness/absence reports and lack of attendance score will result in an 'F' grade: It is for the protection of other attendances in the corresponding course from the frequent absences of the specific/uncertain student(s).
Students are recommended to prepare each lecture by reading the corresponding chapter in the textbook. Also, Students are recommended to review it by solving the related homework questions. Each assignment is due by the start of the next class. Late or no submission of the assignment is the deduction point of the grade.
|Students can communicate with the course instructor face-to-face, either in the class or through the appointment. Communication through emails (instructor's email: jyshin321(at)gamil.com) is also available.
Participants can have the lecture material for each class through NUCT. Sudden questions will be given to students during lectures to provide substantial feedback.