Biochemistry IV(2.0 credits)
|Course Type||:||Specialized Courses|
|Starts 1||:||3 Spring Semester|
|Lecturer||:||NADANO Daita Associate Professor|
|This course is aimed at expanding students’ knowledge in basics of the gene expression and replication from biochemical aspects, including metabolism, structure and molecular function of DNA, RNA and related proteins.
The main goal of this course is for students to understand the structure, synthesis, repair, and recombination of DNA, the synthesis (transcription) and processing of RNA, and the synthesis (translation) and processing of proteins.
|Prerequisite: Biochemistry I, II and III. Basic knowledge of biology and chemistry
Related Courses: Cell Biology I and II, Genetics I and II
|Part V “Gene expression and replication” of the textbook
1. DNA structure
2. DNA synthesis
3. DNA repair and recombination
4. RNA metabolism: transcription and posttranscriptional processing
5. Transfer RNA and ribosomes
6. Translation and posttranslational processing
7. DNA-protein interaction and regulation of gene expression
Students are requested to review after every lecture and submit assignments indicated by the instructors.
|Voet’s Principles of Biochemistry, Global edition, Fifth edition
Voet D, Voet JG, Pratt CW (John Wiley & Sons)
|Molecular Biology of the Cell, Alberts B et al. (Garland Science)|
|Evaluation will be based on examinations at the end of course, and answer/report sheets for Checkpoint at every time of the class. Criteria for “Absent” & “Fail” grades are as follows.
Absent: based on submission of Course Withdrawal Request Form.
Fail: based on failure in the examinations & the answer/report sheets.
|Face-to-face classes (may be changed to on-demand remote classes depending on the status of COVID-19 infection)|
|If you have any questions, please contact the instructor by e-mail.